Sunday, September 15, 2013

La vie est DURham!

                So I feel like I have been living in Durham long enough to talk about it now.  Durham is most definitely a new chapter in my life and, like any new chapter, I was skeptical at first. But things are falling into place and I feel like I can give a more accurate picture of life.  So for those of you who don’t know I started a PhD program at Duke University a few weeks ago in Biochemistry.  Specifically I was accepted into the school through the Structural Biology and Biophysics program.  Structural Biology is essentially studying how all the molecular components of the body (Protein, lipids, DNA, etc.) are formed, shaped and how they operate to preform there tasks within (or sometimes outside) a cell.  Examples include how does a protein help a certain reaction along, or how do cells contract or move.
                This all sounds incredibly interesting in the abstract, and it is, but there are a lot of things that go wrong along the way and to actually observe us in the lab would be a tedious task.  Science is the pursuit of the fascinating through the mundane.  It is necessary to be able to keep a long term perspective and not get discouraged by the fact that most the day may be spent moving liquid A into liquid B, and including powder C in hopes that effect D is observed and recorded by flashing machine E, which most the time it won’t be.  So far I have been able to keep a resolute vision fixed on long-term and unsure achievement for these whole past three weeks.  Only a few years left to go! (I actually am very much enjoying my work; I just want to give an accurate representation of research.  I feel like most people don’t really know what working in a lab is like and have illusions somewhere between Back to the Future’s Doc and the Muppet’s scientist Beaker.)
                Classes are nice and uneventful.  We don’t have any tests as far as I can tell which is nice, just projects and unfortunately I still have homework.  I only have this and next semester where I am required to take classes.  We’ll see how I feel when I get there but the thought of not doing class work is appealing to me.  Most of my degree is based on my research.  For the moment I am doing three rotations of 10 weeks each in three labs before choosing a lab to work in for the rest of my time at Duke.  It is a big commitment that requires the meshing not only scientific interests, but personalities as well with the principal investigator (PI) and the rest of the lab.  I am currently rotating in Pei Zhou’s lab and studying an enzyme that helps make the cell wall of many bacteria.  It could potentially lead to antibiotics or other practical use, but this is basic research.  I am not going to create a wonder-drug or do anything like that in my time at Duke.  In fact many PIs seem almost insulted by the idea that their academic research could have practical implications, unless they are writing grant proposals, but that is another story…
                Myself, long-term I hope to be able to work in “industry” meaning that I would do research for a pharmaceutical company helping them build the next Death Star making millions in the process design new drugs.  I am a long way off and who knows if I will end up on that exact path, but for the moment that is what I sincerely would like to do and will tell my future Father-in-law if I meet him in the next few years.
                As long as we are on the subject, I am enjoying my personal life here.  Grad school has not of yet become all-consuming and for the moment has actually been really nice.  I am enjoying where I live and my roommates are very nice people.  As I plan on posting this online it would be very unwise of me to say otherwise but I do say it with a certain degree of honesty.  The people I work with and go to church with are quite nice as well.  Life is pretty different for me now.  I am living in a town-house about three miles from campus and while there are plenty of students around, there is also families and people from other walks of life.  I feel more settled and less like I’m living in a temporary situation.  My ward (people I go to church with) is very nice.  We have several classes throughout the week that we can attend if we so choose and there are a lot of very neat and rich personalities, which is the case in most wards but is different from my more recent BYU wards.  There are about 100 of us I would guess that come to church.  They are a really welcome and accepting group, which has made my move so much easier.  Thanks to any of them who may read this.
                One last thing of note that I did last weekend was the graduate school campout for basketball tickets.  Basically graduate students hung out in a parking lot from Friday night to Sunday morning to get entered in a lottery to win graduate student tickets to the basketball games (Right under both the baskets).  About 1,200 people did the whole campout and there are 750 tickets so you had a decent shot of winning.  There was a ton more people than that though at the campout however as both nights turned into parties.  It was funny to see those going for the tickets the last night, usually exhausted and not in great shape, and contrast them with those who simply came out for the party and were dressed to impress or drink or whatever they were looking for.  By the end I was pretty out of it.  I didn’t get tickets myself but fortunately the people I was hanging out with from my department did and as they were there just for the experience, they gave me the tickets they won.  Super nice of them and I will have to repay them sometime and somehow.
                That is about it for the first intro to Durham.  Next up I need to actually explore the town a little.  For campout we were actually allowed to leave the parking lot to go do community service and there is a charter school where I went to work that I will try to start volunteering at.   I want to reach out to the community and give back and all those things, it would look great on grant applications.  Hopefully I don’t get too drowned in graduate work in the near future.  But until then best wishes to everyone reading and know that I’m doing great!